QuizWise 76

Question 1. Lattice corneal dystrophy occurs at which layer of cornea:
A) Epithelium
B) Stroma
C) Endothelium
D) Epithelial-Stromal 

Answer: D) Epithelial-stromal

Lattice corneal dystrophy is classified as an epithelial stromal dystrophy. Other epithelial stromal dystrophies include Reis Buckler’s dystrophy, Thiel-Behnke dystrophy and Granular dystrophy.


Weiss JS, Møller HU, Aldave AJ, Seitz B, Bredrup C, Kivelä T, Munier FL, Rapuano CJ, Nischal KK, Kim EK, Sutphin J, Busin M, Labbé A, Kenyon KR, Kinoshita S, Lisch W. IC3D classification of corneal dystrophies–edition 2. Cornea. 2015 Feb;34(2):117-59. https://core.ac.uk/reader/154266722?utm_source=linkout

Question 2. Which is correct regarding order of recurrence in corneal graft for corneal dystrophies:
A) Reis Buckler > Lattice > Granular > Macular
B) Lattice > Reis Buckler > Granular > Macular
C) Reis Buckler  > Granular > Lattice > Macular
D) Macular > Reis Buckler > Lattice > Granular 

Answer: C) Reis Buckler  > Granular > Lattice > Macular

5 year follow up has shown that corneal dystrophy of Bowman membrane (Which includes Reis Buckler dystrophy) shows highest rate of recurrence (88.2 %) followed by granular (40%) followed by lattice dystrophy (17.8%). Recurrence was found to be infrequent in macular corneal dystrophy.


Marcon AS, Cohen EJ, Rapuano CJ, Laibson PR. Recurrence of corneal stromal dystrophies after penetrating keratoplasty. Cornea. 2003 Jan 1;22(1):19-21. https://journals.lww.com/corneajrnl/Abstract/2003/01000/Recurrence_of_Corneal_Stromal_Dystrophies_After.5.aspx

Question 3. Which stain is used to identify LCD:
A) Alcian blue
B) Congo red
C) Masson Trichrome
D) None of the above 

Answer: B) Congo red

Congo red stains amyloid which forms the lattices in LCD. Alcian blue stains glycosaminoglycans found in Macular corneal dystrophy. Masson trichrome stains hyaline found in Granular corneal dystrophy.

Moshirfar M, West W, Ronquillo Y. Lattice Corneal Dystrophy. https://europepmc.org/article/MED/32310559/NBK430685#free-full-text

Question 4. Not a treatment for LCD?
A) Photherapeutic keratectomy
B) Deep anterior lamellar keratoplasty
C) Penetrating keratoplasty
D) Descemet stripping endothelial keratoplasty 

Answer: D) Descemet stripping endothelial keratoplasty

Lattice corneal dystrophy can be treated by DALK, PKP or PTK. DSEK is done for endothelial dystrophies eg. Fuchs endothelial dystrophy


Moshirfar M, West W, Ronquillo Y. Lattice Corneal Dystrophy.  https://europepmc.org/article/MED/32310559/NBK430685#free-full-text

Question 5. Which is not a cause of recurrent corneal erosions?
A) Fuchs endothelial dystrophy
B) Lattice corneal dystrophy
C) Granular dystrophy
D) Reis Buckler dystrophy

Answer: A) Fuchs endothelial dystrophy

Recurrent corneal erosions are seen in Lattice dystrophy,  Granular dystrophy, Macular dystrophy, Map dot fingerprint dystrophy & Reis Buckler dystrophy .


Lin SR, Aldave AJ, Chodosh J. Recurrent corneal erosion syndrome. British Journal of Ophthalmology. 2019 Sep 1;103(9):1204-8. https://bjo.bmj.com/content/103/9/1204.abstract

You cannot copy content of this page

× Hello!
%d bloggers like this: