Meibomian Gland Dysfunction (MGD) and Blepharitis
MGD & Blepharitis
This patient-education article is written by the cornea service at Suraj Eye Institute, Nagpur.
What is MGD and Blepharitis?
Blepharitis is chronic inflammation of the eyelid margins. Meibomian gland dysfunction (MGD) is a specific, very common form in which the meibomian glands — the rows of tiny oil glands inside the eyelids that secrete the lipid layer of the tear film — become blocked, inflamed or atrophied. MGD is the leading cause of evaporative dry eye.
Symptoms
Patients describe a chronic gritty, burning sensation, red lid margins, crusting of the lashes on waking, and watery, fluctuating vision. Recurrent styes (hordeola) and chalazia indicate poorly controlled MGD. Symptoms typically worsen with screen use and in dry environments.
How MGD is Diagnosed
Diagnosis is clinical. We examine the lid margin at the slit-lamp for thickened, telangiectatic edges, capped or plugged gland orifices, and the quality of expressed meibum. Meibography quantifies how much of the gland tissue remains.
Treatment
MGD is chronic and the aim is long-term control. Most patients respond well to a structured combination of measures:
- Warm compresses for 5–10 minutes daily (a heated eye mask is more effective than a face cloth)
- Lid hygiene — gentle lid margin cleaning with a dedicated lid wipe or diluted baby shampoo
- Omega-3 supplements at adequate dose, improving meibum quality over weeks to months
- Topical azithromycin or low-dose oral doxycycline / azithromycin courses to reduce inflammation
- Intense pulsed light (IPL) therapy for refractory MGD, particularly when ocular rosacea is present
- In-clinic meibomian gland expression after warming for severely capped glands
We offer structured assessment of the lid margin, infrared meibography to image gland drop-out, and a stepped treatment approach including warm-compress devices, microblepharo-exfoliation, topical azithromycin, oral doxycycline and intense pulsed light (IPL) therapy for refractory MGD.
Frequently Asked Questions
